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. 2020 Nov 23;12(23):23464–23477. doi: 10.18632/aging.104148

Table 5. Demographic and characteristics of COVID-19 patients with or without cardiac injury.

Patients, No, (%) P value
All (n=113) Cardiac injury
Without (n=95) With (n=18)
Severity 0.018
Non-severe patients 60 (53.1%) 55 (57.9%) 5 (27.8%)
Severe patients 53 (46.9%) 40 (42.1%) 13 (72.2%)
Characteristics
Age, years 63.00 (49.50-70.00) 62.00 (48.00-69.00) 69.50 (66.50-78.00) < 0.001
Sex 0.202
Man 62 (54.9%) 45 (47.4%) 6 (33.3%)
Women 51 (45.1%) 50 (52.5%) 12 (66.7%)
Any comorbidity
Hypertension 28 (24.8%) 19 (20.0%) 9 (50.0%) 0.011
Diabetes 15 (13.3%) 12 (12.6%) 3 (16.7%) 0.441
Surgery history 11 (9.7%) 9 (9.5%) 2 (11.1%) 0.553
Others 22 (19.5%) 16 (16.8%) 6 (33.3%) 0.101
Signs and symptoms
Fever 89 (78.8%) 73 (76.8%) 16 (88.9%) 0.207
Time of fever, day 10.00 (4.50-15.00) 10.00 (4.00-15.00) 10.00 (7.00-14.25) 0.773
Highest temperature, °C 0.716
< 37.3 32 (28.3%) 26 (27.4%) 6 (33.3%)
37.3-38.0 27 (23.9%) 23 (24.2%) 4 (22.2%)
38.1-39.0 42 (37.2%) 36 (37.9%) 6 (33.3%)
> 39.0 12 (10.6%) 10 (10.5%) 2 (11.1%)
Respiratory rate 20.00 (19.00-22.00) 20.00 (19.00-21.00) 21.50 (19.00-29.00) 0.053
Heart rate, time per s 89.55±18.52 87.86±17.22 98.44±22.83 0.026
Systolic pressure, mm Hg 133.87±17.16 131.75±15.49 145.06±21.35 0.002
Cough 68 (60.2%) 58 (61.1%) 10 (55.6%) 0.426
Sputum production 32 (28.3%) 27 (28.4%) 5 (27.8%) 0.601
Myalgia or fatigue 49 (43.4%) 40 (42.1%) 9 (50.0%) 0.357
Headache 4 (3.5%) 3 (3.2%) 1 (5.6%) 0.506
Chest distress 31 (27.4%) 28 (29.5%) 3 (16.7%) 0.207
Dyspnea 32 (28.3%) 27 (28.4%) 5 (27.8%) 0.601
Diarrhea 13 (11.5%) 10 (10.5%) 3 (16.7%) 0.342
PSI score 68.67±31.51 64.78±32.58 89.22±16.01 < 0.001
CURB65 score 0.81±0.79 0.72±0.78 1.33±0.59 < 0.001
APACHE-II score 6.20±4.36 5.56±4.31 9.56±2.83 < 0.001
SOFA score 2.00 (1.00-3.00) 1.00 (1.00-2.00) 3.00 (2.00-4.00) < 0.001
Clinical outcome
The length of hospital days 26.05±12,92 25.40±13.34 30.21±9.11 0.100
Mortality 9 (8.0%) 5 (5.3%) 4 (22.2%) 0.035

Data are median (IQR), mean±SEM, n (%), or n/N (%). p values were calculated by Mann-Whitney U test, t test, χ2 test, or Fisher's exact test, as appropriate. Abbreviation: PSI score, pneumonia severity index score; CURB 65 score, Confusion/Urea/Respiratory rate/Blood pressure 65; APACHE-II score, Acute Physiology and Chronic Health Evaluation II score; SOFA score, Sequential Organ Failure Assessment score.

χ2 test comparing all subcategories.