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. 2020 Nov 23;12(23):23464–23477. doi: 10.18632/aging.104148

Table 6. Laboratory indicators of COVID-19 patients with or without cardiac injury.

Patients, No, (%) P value
All (n=113) Cardiac injury
Without (n=95) With (n=18)
White blood cell × 109 per L 6.76±3.30 6.64±3.15 7.41±4.01 0.383
Neutrophil 3.89 (2.67-7.00) 3.81 (2.41-6.36) 5.44 (3.07-8.41) 0.166
Lymphocytes 1.10±0.57 1.17±0.59 0.78±0.26 < 0.001
Monocytes 0.46±0.21 0.47±0.22 0.41±0.18 0.253
Platelet count, × 109 per L 226.71±85.51 236.57±83.70 180.17±80.45 0.010
Red cell count, × 109 per L 4.14±0.59 4.16±0.61 4.04±0.49 0.130
Haemoglobin, g/L 128.00 (120.00-137.75) 128.00 (119.75-138.25) 130.00 (120.25-138.00) 0.997
Albumin, g/L 37.86±5.96 38.33±5.72 35.49±6.74 0.072
CRP mg/L 35.80 (5.00-87.18) 25.00 (5.00-77.50) 63.50 (24.70-154.20) 0.004
ALT, U/L 24.00 (17.00-42.00) 23.00 (17.00-40.25) 32.00 (19.75-71.50) 0.101
TB, mmol/L 12.00 (8.90-15.80) 11.35 (8.50-15.15) 15.50 (11.85-25.80) 0.010
Potassium, mmol/L 4.08±0.65 4.16±0.64 3.7±0.601 0.010
Sodium, mmol/L 141.68±5.09 142.02±4.82 139.94±6.16 0.124
Calcium, mmol/L 2.13 (2.03-2.22) 2.15 (2.06-2.25) 2.03 (1.97-2.09) 0.001
Creatinine, μmol/L 63.00 (53.00-74.00) 62.00 (53.00-74.00) 64.00 (53.50-71.50) 0.616
IL2, pg/L 3.59 (3.17-3.98) 3.56 (3.17-4.12) 3.67 (3.17-3.98) 0.045
IL4, pg/L 3.20±0.63 3.09±0.70 3.31±0.53 0.396
IL6, pg/L 10.20 (5.77-37.20) 6.49 (4.34-11.94) 16.38 (7.65-0.98) 0.003
IL10, pg/L 5.85 (4.64-7.60) 5.30 (4.32-6.21) 6.19 (5.24-12.16) 0.119
TNF-α, pg/L 3.18 (2.68-5.35) 3.01 (2.59-5.71) 3.21 (2.75-5.59) 0.827
INF-γ, pg/L 3.44 (3.01-5.24) 3.42 (2.82-5.38) 3.44 (3.11-4.29) 0.468
LDH, U/L 313.22±153.57 290.45±142.20 443.73±155.72 < 0.001
BNP, pg/mL 144.50 (51.58-369.08) 95.39 (26.66-227.38) 553.10 (299.83-1179.00) < 0.001
CK, U/L 58.00 (40.00-103.00) 53.50 (37.75-86.25) 119.00 (72.00-168.00) < 0.001
CKMB, U/L 1.13 (0.64-1.72) 1.02 (0.62-1.46) 2.31 (1.42-3.53) < 0.001
D-dimer, mg/L 0.81 (0.36-2.30) 0.63 (0.34-1.88) 3.20 (1.03-15.04) 0.003
Procalcitonin, ng/mL 0.43 (0.13-3.80) 0.55 (0.13-4.45) 0.39 (0.11-1.20) 0.273

Data are median (IQR), mean±SEM. p values were calculated by Mann-Whitney U test or t test as appropriate. Abbreviation: CRP, C-reactive protein; ALT, alanine aminotransferase; TB, total bilirubin; LDH, lactate dehydrogenase; cTnI, cardiac troponin I; BNP, brain natriuretic peptide; CK, creatine kinase; CKMB, creatine kinase-MB.