Table 1. The univariate and multivariate COX regression analysis of m6A regulatory genes for patients' overall survival (OS) in endocrine system tumors.
Cancer types | Univariate | Multivariate | |||
HR (95%CI) | P | HR | P | ||
ACC | gender | 1.100591489 | 0.814544864 | 1.038052354 | 0.930365584 |
stage | 2.760634449 | <0.01 | 0.732881514 | 0.571016476 | |
T | 3.237383176 | <0.01 | 3.747329892 | 0.005749074 | |
N | 1.829492414 | 0.269274473 | 2.918855029 | 0.137599231 | |
riskScore | 1.193940656 | <0.01 | 1.13395091 | 0.010312723 | |
PCPG | gender | 3.131482468 | 0.198106512 | 10.54784495 | 0.0623891 |
riskScore | 1.001445171 | 0.004298715 | 1.002063944 | 0.001882145 | |
THCA | age | 1.155357049 | <0.01 | 1.166359177 | 0.000826538 |
gender | 0.868700107 | 0.860752257 | 0.731485506 | 0.748013828 | |
stage | 2.729834716 | 0.002868951 | 0.796474584 | 0.823787006 | |
T | 2.4428418 | 0.028302365 | 2.563634273 | 0.295472549 | |
M | 2.560644338 | 0.379583475 | 3.906592763 | 0.292240082 | |
N | 2.086807866 | 0.298770285 | 0.388357974 | 0.367125281 | |
riskScore | 1.020547508 | 0.014232509 | 1.015493346 | 0.147944117 | |
THYM | gender | 0.629466902 | 0.49190441 | 0.66426715 | 0.550430644 |
riskScore | <0.01 | 0.000837672 | >1 | 0.000987518 | |
Total1 | gender | 1.596802381 | 0.15281085 | 1.342885697 | 0.38062215 |
stage | 2.73244358 | <0.01 | 2.124943581 | 0.002348671 | |
T | 3.351611782 | <0.01 | 1.668245363 | 0.051414123 | |
N | 0.616791825 | 0.152388789 | 0.400896738 | 0.011567273 | |
riskScore | 164.1049178 | <0.01 | 47.82932365 | <0.01 | |
Total2 | gender | 1.271577618 | 0.642975417 | 1.180127876 | 0.749370968 |
riskScore | 414.944273 | 0.012117844 | 407.8618477 | 0.01288766 |
Note: Ambiguous variables (Nx, Mx, N/A, discrepancy and Gx) were excluded. ACC, Adrenal cortical carcinoma;
PCPG, Pheochromocytoma and Paraganglioma; THCA, Thyroid carcinoma; THYM, Thymoma;
Total1, Adrenal cortical carcinoma and Thyroid carcinoma; Total2, Pheochromocytoma and Paraganglioma and Thymoma.