Table 1.
Formulation Liposome Composition (mol ratio) |
Empty-CL | CWS-Nano-CL | CWS-Nano-CL-chitosan |
---|---|---|---|
PC | 90 | 90 | 90 |
CH | 10 | 10 | 10 |
Physical properties | |||
Size (nm) | 185.1 ± 0.19 | 187.2 ± 0.19 | 196.33 ± 0.34 |
PDI | 0.11 ± 0.05 | 0.13 ± 0.04 | 0.16 ± 0.03 |
ZP (mV) | −8.26 ± 0.17 | −8.31 ± 0.37 | 33.17 ± 0.24 |
EE (%) | 60.15 ± 0.28 | 58.25 ± 0.31 | |
DL | 219.87 ± 4.69 | 217.91 ± 3.29 |
Data represent the mean ± SD (n = 3). PC, phosphatidylcholine; CH, cholesterol; PDI, polydispersity index; ZP, zeta potential; EE, entrapment efficiency; DL, drug loading; CWS, chitosan.