Table 1.
Virus recovery in tracheal and cloacal swabs and antibody response in the serum of the chickens treated with different doses of BXM at single administration.
Treatment (mg/kg) | Chicken ID | Virus Recovery from Swabs on Days Post-Challenge (log10 EID50/mL) a | HI Titer in Serum b | |||||
---|---|---|---|---|---|---|---|---|
0 | 3 | 5 | 7 | 14 | 0 | 14 | ||
T/C | T/C | T/C | T/C | T/C | ||||
# 41 | –/– | 5.2/4.8 | † | † | † | <2 | † | |
Control | # 42 | –/– | 4.9/4.0 | † | † | † | <2 | † |
# 45 | –/– | 5.5/4.3 | † | † | † | <2 | † | |
# 46 | –/– | 5.3/4.5 | † | † | † | <2 | † | |
0.1 | # 1 | –/– | 4.2/3.5 | † | † | † | <2 | † |
# 2 | –/– | –/– | –/– | –/– | –/– | <2 | 64 | |
# 5 | –/– | 3.8/2.7 | † | † | † | <2 | † | |
# 6 | –/– | 4.2/3.5 | † | † | † | <2 | † | |
0.5 | # 9 | –/– | 3.4/2.7 | † | † | † | <2 | † |
# 10 | –/– | 3.5/3.5 | 3.7/3.2 | † | † | <2 | † | |
# 13 | –/– | 3.2/3.0 | 2.6/3.0 | † | † | <2 | † | |
# 14 | –/– | –/– | –/– | –/– | –/– | <2 | 64 | |
2.5 | # 17 | –/– | –/– | –/– | –/– | –/– | <2 | 64 |
# 18 | –/– | –/– | –/– | –/– | –/– | <2 | 64 | |
# 21 | –/– | –/– | –/– | –/– | –/– | <2 | 64 | |
# 22 | –/– | –/– | –/– | –/– | –/– | <2 | 64 | |
12.5 | # 25 | –/– | –/– | –/– | –/– | –/– | <2 | 32 |
# 26 | –/– | –/– | –/– | –/– | –/– | <2 | 64 | |
# 29 | –/– | –/– | –/– | –/– | –/– | <2 | 64 | |
# 30 | –/– | –/– | –/– | –/– | –/– | <2 | 64 | |
62.5 | # 33 | –/– | –/– | –/– | –/– | –/– | <2 | 64 |
# 34 | –/– | –/– | –/– | –/– | –/– | <2 | 64 | |
# 37 | –/– | –/– | –/– | –/– | –/– | <2 | 64 | |
# 38 | –/– | –/– | –/– | –/– | –/– | <2 | 64 |
a The virus titer in tracheal and cloacal swab; (#) indicates the identification for each chicken; (–/–) indicates under detection limit (0.5 log10 EID50/mL) for both T and C swab supernatant.; b The antibody titer in the serum before and after infection.; (†) indicates that chicken died during the observation period; (T) and (C) indicate tracheal and cloacal swabs, respectively.