Figure 1.

iPSC derived from SAD. iPSCs are similar to embryonic stem cells (ESCs) in morphology (a), which are characterized by colony-like growth, compact and tidy edges, small size, and high nuclear-cytoplasmic ratio. AP staining of iPSC-22-1 and iPSC-15-5 is positive (b). Specific protein expression of ESC was used to detect the immunofluorescence reaction of iPSC (c). The karyotype of iPSC was detected by karyotype analysis (d). The karyotypes of iPS-22-1 were 46, XX and those of iPS-15-5 were 46, XX. Both strains were normal cell karyotypes.