Choices in the Cognitive and Physical Effort Tasks (Mean ± 1 SEM)
Acceptance rates for the higher-effort/higher-reward offer are plotted as a function of effort (left column) and reward (center column). Difference plots illustrate choice differences between controls and pre-manifest HD across the two-dimensional effort-reward space (right column). Red indicates greater motivation in controls than pre-manifest HD.
(A) For cognitive-effort-based choices, pre-manifest HD was less willing to accept the higher-effort/higher-reward offers.
(B) For the physical-effort-based choices, decisions were similar between groups.
See also Figures S1 and S2.