Fig. 2.

There is synergy between phage cocktail and meropenem when used to prevent biofilm formation. Phage treatments when added at the start (A), as a biofilm prevention strategy, or for 5 ​h (B) to the mature Klebsiella biofilms as described in the methods. Biofilms were analysed using the resazurin viability stain. Klebsiella strain 170723 had no significant reductions in biofilm viability, however all other strains showed some reductions, and there appeared to be a synergistic effect when used in combination with meropenem. Symbols denote significant difference (t-test); ∗ compared to positive control, # compared to corresponding phage cocktail treatment, and ~ compared to corresponding meropenem treatment. ∗/#/~ denotes p value ​≤ ​0.05, ∗∗/##/~~, p ​≤ ​0.01, ∗∗∗/###/~~~, p ​≤ ​0.001.