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. 2020 Dec 26;82(3):170–176. doi: 10.1016/j.humimm.2020.12.010

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© 2020 Published by Elsevier Inc. on behalf of American Society for Histocompatibility and Immunogenetics.

Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

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Fig. 5 — Dynamic changes of monocytes in COVID-19 patients during recovery. (A–C) The absolute number of total monocytes, CD16⁻ monocytes and CD16⁺ monocytes in COVID-19 patients with mild, severe and critical illness during recovery. (D, E) The expression of HLA-DR and CD38 on monocytes in COVID-19 patients with mild, severe and critical illness as the disease went into remission. (A–E) With one critical patient’s disease progression before death, the dynamic changes of the absolute number of monocytes, CD16⁻ monocytes and CD16⁺ monocytes and the expression of HLA-DR and CD38 expression on monocytes. Mild patients (green line), severe patients (blue line), critical patients (grey line), one critical patient before death (red line). The X-axis coordinates represented days of admission to hospital of COVID-19 patients for treatment. Except for the red line, every other line represented the average of patient data. The red line represented the dynamic changes of monocytes in one critical patient before death. Selected randomly several patients in each group, including 8 mild cases, 4 severe cases, 4 critical cases and one critical patient before death. *, P < 0.05; **, P < 0.01; ***, P < 0.001; ****, p < 0.0001. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)