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. 2020 Oct 14;295(51):17646–17658. doi: 10.1074/jbc.RA120.015492

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© 2020 Teng et al.

Published under exclusive license by The American Society for Biochemistry and Molecular Biology, Inc.

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Figure 3. — HRDC suppresses the duplex unwinding activity of RecQ. A, fractions of remaining 16 bp 12 nt-1 molecules on coverslip versus time after addition of 5 nm RecQ and 20 µm ATP. Lines are the simple connections of the individual data points by Origin 8.0. B, the initiation time of 16 bp 12 nt-1 in 5 nm RecQ, RecQ⁵²³, and RecQ^Y555A in different concentrations of ATP. C, the fractions of 16 bp 12 nt-2 traces showing one-step unwinding in 5 nm RecQ, RecQ⁵²³, and RecQ^Y555A in different concentrations of ATP.