Table 1.

Comparison of bench top second-generation sequencers as well as some of PacBio’s and ONT’s platforms.

Sequencing Platform	Read Length	Data Output	Run Time	Single-Pass Error Rate (%)	Reference
Illumina Hiseq 2000	2 × 150 bp	150–200 Gb	1–6 days	0.16	[70,71]
Illumina NextSeq 550	2 × 150 bp	120 Gb	15–18 h	0.16	[70,71]
Pacbio RS II	10–15 kb on average	0.5–1 Gb	0.5–4 h	10	[16,71]
PacBio Sequel	10–15 kb on average	15 Gb	Up to 20 h	10	[72]
PacBio Sequel II	10–15 kb on average	80–100 Gb	Up to 30 h	10	[73]
Oxford Nanopore MinION	10–20 kb on average	20–30 Gb (per flow cell) Up to 1 flow cell/run	Up to 96 h	5–20	[12,74]
Oxford Nanopore GridION	10–20 kb on average	20–30 Gb (per flow cell) Up to 5 flow cells/run	Up to 96 h	5–20	[12,74]
Oxford Nanopore PromethION	10–20 kb on average	100–180 Gb (per flow cell) Up to 48 flow cells/run	Up to 96 h	5–20	[12,74]