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. 2020 Dec 11;12(12):1204. doi: 10.3390/pharmaceutics12121204

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Histological sections of the groups (wounded areas) of the wound-healing biological assay over a course of time. An intense inflammatory response and edema are observed in the CTR (a) and GEL (b), while immature granulation tissue is observed in GELPG at day 3 (c). Well-vascularized granulation tissue is observed in the CTR (d) and GEL (e) at day 7, while fibrous connective tissue was formed in GELPG (f). Primary fibrous scars can be seen in all of the groups at day 14 (g–i), though hair follicles already began forming in GELPG (I). Dense fibrous connective tissue is seen in all the groups at day 21 (j–l), with multiple hair follicles observed in GELPG (l) (HE, 40/400× magnification).