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. 2020 Dec 8;21(24):9346. doi: 10.3390/ijms21249346

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© 2020 by the author.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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A model of erythropoiesis in the yolk sac. Timeline of erythropoiesis is schematically described along with the embryonic day of mouse development (E7–E9). Representative marker expression is shown along with the cell population names. Periods when each cell population are present are shown by horizontal bars. EryP, primitive erythrocytes; EryD, definitive (adult-type) erythrocytes; HEC, hemogenic endothelial cells; CPDP; common primitive-definitive precursors; MRP, myeloid-restricted progenitors; EMP, erythroid-myeloid progenitors; MLMP, multipotent lympho-myeloid progenitors.