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. 2020 Dec 12;8(12):598. doi: 10.3390/biomedicines8120598

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Nitric oxide release from infected murine macrophages in presence and absence of uric acid. Murine RAW264.7 macrophages were infected with formalin-fixed bacteria in presence and absence of soluble uric acid (19 mg/dL) and incubated overnight. Nitric oxide release in the supernatants was quantitated using the Griess method. These data represent the mean of six independent experiments with bars showing the standard error of the mean. KPS: K. pneumoniae sensitive to antibiotics; KPR: K. pneumoniae resistant to antibiotics; SA: S. aureus; MRSA LR: methicillin-resistant S. aureus with low level of resistance; MRSA HR: methicillin-resistant S. aureus with high level of resistance; UA: uric acid; ns: not significant. p value < 0.05 are significant.