Table 1.
Clinical and pathologic characteristics of tumor samples from patients with IBC according to NDRG1 expression.
| Covariate | Level | NDRG1-Low (n = 32) |
NDRG1-High (n = 32) |
p-Value |
|---|---|---|---|---|
| Age | 51.5 ± 12.1 | 48.6 ± 12 | 0.3861 | |
| Race | Non-white | 8 (25%) | 5 (16%) | 0.5356 |
| White | 24 (75%) | 27 (84%) | ||
| Histologic type | Others | 2 (6%) | 4 (13%) | 0.6719 |
| Ductal | 30 (94%) | 28 (87%) | ||
| Grade | 1–2 | 6 (19%) | 7 (22%) | 0.7560 |
| 3 | 26 (81%) | 25 (78%) | ||
| Lymphovascular invasion | No | 4 (14%) | 3 (10%) | 0.7065 |
| Yes | 25 (86%) | 27 (90%) | ||
| Stage | III | 31 (97%) | 27 (84%) | 0.1961 |
| IV | 1 (3%) | 5 (16%) | ||
| Estrogen receptor | No | 21 (66%) | 19 (61%) | 0.7209 |
| Yes | 11 (34%) | 12 (39%) | ||
| Progesterone receptor | No | 24 (75%) | 19 (61%) | 0.2425 |
| Yes | 8 (25%) | 12 (39%) | ||
| HER2 | No | 12 (37%) | 22 (71%) | 0.0077 |
| Yes | 20 (63%) | 9 (29%) | ||
| Triple-negative breast cancer | No | 27 (84%) | 20 (64%) | 0.0879 |
| Yes | 5 (16%) | 11 (36%) | ||
| Adjuvant radiation | No | 10 (31%) | 11 (34%) | 0.7901 |
| Yes | 22 (69%) | 21 (66%) |