Table 2.
Univariate Cox regression analysis on overall survival and disease-specific survival among patients with IBC.
| Overall Survival | Disease-Specific Survival | ||||||
|---|---|---|---|---|---|---|---|
| Covariate | Level | HR | 95% CI | p-Value | HR | 95% CI | p-Value |
| Age | 1 Unit Change | 1.007 | 0.980–1.035 | 0.6080 | 1.000 | 0.971–1.029 | 0.9904 |
| NDRG1 | Low | 1.000 | 1.000 | ||||
| High | 2.107 | 1.155–3.842 | 0.0150 | 2.354 | 1.235–4.485 | 0.0092 | |
| Race | Non-white | 1.000 | 1.000 | ||||
| White | 1.823 | 0.769–4.321 | 0.1724 | 1.940 | 0.757–4.973 | 0.1676 | |
| Histologic type | Others | 1.000 | 1.000 | ||||
| Ductal | 1.027 | 0.368–2.870 | 0.9591 | 1.153 | 0.410–3.243 | 0.7874 | |
| Grade | 1–2 | 1.000 | 1.000 | ||||
| 3 | 2.404 | 1.014–5.698 | 0.0463 | 2.612 | 1.020–6.688 | 0.0453 | |
| Lymphovascular invasion | No | 1.000 | 1.000 | ||||
| Yes | 1.684 | 0.601–4.717 | 0.3216 | 1.493 | 0.529–4.213 | 0.4486 | |
| Stage | III | 1.000 | 1.000 | ||||
| IV | 4.638 | 1.847–11.647 | 0.0011 | 5.485 | 2.138–14.069 | 0.0004 | |
| Estrogen receptor | No | 1.000 | 1.000 | ||||
| Yes | 0.414 | 0.212–0.808 | 0.0098 | 0.426 | 0.211–0.860 | 0.0173 | |
| Progesterone receptor | No | 1.000 | 1.000 | ||||
| Yes | 0.699 | 0.359–1.361 | 0.2919 | 0.816 | 0.412–1.616 | 0.5598 | |
| HER2 | No | 1.000 | 1.000 | ||||
| Yes | 0.748 | 0.409–1.366 | 0.3445 | 0.602 | 0.313–1.161 | 0.1300 | |
| Triple-negative breast cancer | No | 1.000 | 1.000 | ||||
| Yes | 1.557 | 0.810–2.992 | 0.1844 | 1.692 | 0.852–3.358 | 0.1328 | |
| Adjuvant radiation | No | 1.000 | 1.000 | ||||
| Yes | 0.538 | 0.295–0.982 | 0.0434 | 0.486 | 0.259–0.914 | 0.0252 | |