Table 2.
Effects of gallic acid on oxidative stress markers of rat’s embryonic fibroblast and pancreatic islet cells.
| Oxidative Stress Markers | Pancreatic Islet Cells | Embryonic Fibroblast Cells | |||||
|---|---|---|---|---|---|---|---|
| Control (Mean ± SE) |
GA (Mean ± SE) |
Control (Mean ± SE) |
H2O2 (Mean ± SE) |
GA (Mean ± SE) |
GA + H2O2 (Mean ± SE) |
||
| 1 | ROS (mole/min.mg protein) | 679.50 ± 41.54 | 99.10 ± 3.13 aaa | 1.94 ± 0.18 | 4.03 ± 0.23 aaa | 1.85 ± 0.09 bbb | 2.54 ± 0.06 bbb |
| 2 | LPO (µM) | 1.43 ± 0.01 | 1.22 ± 0.01 aaa | 109.99 ± 4.24 | 178.80 ± 4.76 aaa | 91.00 ± 4.17 abbb | 132.80 ± 2.33 aabbb |
| 3 | FRAP (mM) | 56.60 ± 0.73 | 106.83 ± 1.09 aaa | 160.84 ± 1.96 | 87.79 ± 2.70 aaa | 155.84 ± 4.17 bbb | 113.79 ± 1.86 aaabb |
| 4 | Thiol (µmole/mg protein) | 3.00 ± 0.07 | 5.00 ± 0.11 aaa | 60.39 ± 3.12 | 35.96 ± 3.01 aa | 65.98 ± 8.40 b | 54.28 ± 3.84 b |
Abbreviations: FRAP: ferric reducing antioxidant power; LPO: lipid peroxidation; ROS: reactive oxygen species. Data are presented as the mean ± standard error of measurements performed on six groups, with three independent replicates. Significant difference from control (a p < 0.05, aa p < 0.01, and aaa p < 0.001), significant difference from H2O2 (b p < 0.05, bb p < 0.01, and bbb p < 0.001).