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. 2020 Dec 8;9(12):3978. doi: 10.3390/jcm9123978

Table 5.

IOP lowering effects of intravenous cannabinoids.

Authors Patient Population Intervention Results
Purnell et al., 1975 [74] 2 healthy subjects Single dose of 6.7 mg THC in subject 1 62% IOP lowering 90 min after administration
Single dose of 3.0 mg THC in subject 2 42% IOP lowering 30 min after administration
Cooler et al., 1976 [75] 10 healthy subjects 0.022 mg/Kg delta-9-THC 29% IOP lowering
0.044 mg/Kg delta-9-THC 37% IOP lowering

IOP: intraocular pressure, THC: Tetrahydrocannabinol.