Table 6.
Adjusted Risk of Mortality on the Wait List by Diagnosis and MSC Use
| Variable | Hazard Ratio | 95% CI | P Value |
|---|---|---|---|
| Parametric hazard modeling results for CHD | |||
| Race (White) | 0.76 | 0.60–1.0 | 0.04 |
| List year (since 2010) | 0.92 | 0.88–0.96 | 0.0004 |
| ECMO | 4.40 | 3.30–5.85 | <0.0001 |
| VAD | 2.46 | 1.65–3.66 | <0.0001 |
| Weight at listing, kg | 0.94 | 0.88–1.00 | 0.05 |
| Status 1A at listing | 2.04 | 1.27–3.28 | 0.003 |
| Ventilator at listing | 1.54 | 1.18–2.01 | 0.001 |
| Parametric hazard modeling results for cardiomyopathy | |||
| ECMO | 3.48 | 2.16–5.60 | <0.0001 |
| VAD | 1.83 | 1.18–2.86 | 0.008 |
| Ventilator at listing | 1.79 | 1.20–2.68 | 0.005 |
| Parametric hazard modeling results for ECMO | |||
| List year (since 2010) | 0.89 | 0.82–0.96 | 0.002 |
| CHD | 2.7 | 1.75–4.16 | <0.0001 |
| Parametric hazard modeling results for VAD | |||
| Weight at listing (logarithmic), kg | 0.324 | 0.17–0.62 | 0.0006 |
| CHD | 2.19 | 1.31–3.66 | 0.003 |
Patients are in >1 cohort. CHD indicates congenital heart disease; ECMO, extracorporeal membrane oxygenation; MSC, mechanical circulatory support; and VAD, ventricular assist device.