Skip to main content
. 2020 Oct 22;9(21):e017748. doi: 10.1161/JAHA.120.017748

Figure 5. RBC storage age is associated with an increased AV node effective refractory period.

Figure 5

A, Biosignals recorded with atrial pacing (S1–S2) to pinpoint AVNERP in the presence of day 7 sRBC, (B) day 40 sRBC, or (C) 10 mM K+. D, AVNERP did not change after exposure to day 7–30 sRBC, but increased with day 40 and day 50 sRBC exposure. E, AVNERP increased with severe hyperkalemia. Arrowheads denote ventricular response to atrial pacing at S1 (black) or S2 (gray) pacing cycle length. ≠ denotes failed conduction. Mean±SEM, *P<0.05, n=3–6. AVNERP indicates atrioventricular node effective refractory period; RBC, red blood cell; sRBC, supernatant from red blood cell units.