Table 4.
Comparison between patient A and Bradley´s Group #4.
| AUC06,SSmicrog/h/mL Median (Range) |
t1/2 (h) | Vd (L/kg) | CLRenal (L/kg/h) | |
|---|---|---|---|---|
| Patient A (dose: 40 mg/kg) |
397.73 | 3.51 | 0.505 | 0.101 |
| Bradley Group 4 (dose: 30 mg/kg) Mean (CV%) (SD lower-upper limits) |
202 (158–259) |
1.63 (69%) (0.51–2.75) |
0.34 (21.1%) (0.27–0.41) |
0.149 (43.2%) (0.085–0.213) |
AUC: area under curve at steady-state; t1/2,β: terminal half-life; Vd volume of distribution: CLRenal renal clearance; CV: coefficient of variance; SD: standard deviation.