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. 2020 Dec 23;5(6):e01221-20. doi: 10.1128/mSphere.01221-20

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Copyright © 2020 Lu et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.

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FIG 1 — Sequence comparison of plasmids harboring the mcr-1 gene. (a) Circular comparison between mcr-1-bearing IncI2 plasmid pLD67-1-MCR1 in strain LD67-1 in this study and three similar IncI2 plasmids in the NCBI nr database. pLD67-1-MCR1 was used as the reference in the outermost ring. (b) Circular comparison between mcr-1-carrying IncX4 plasmid pLD93-1-MCR1 in strain LD93-1 in this study and two similar IncX4 plasmids in the NCBI nr database. The outer circle with red arrows denotes annotation of reference plasmid pLD93-1-MCR1. (c) Circular comparison between three mcr-1-bearing IncHI2 plasmids and two similar IncHI2 plasmids in the NCBI nr database. (d) Linear comparison of the partial sequence containing mcr-1 of IncHI2 type plasmids (pLD22-1, pLD26-1, and pLD39-1) with two similar structures of plasmids pMCR_WCHEC050613 and p14EC029b in the NCBI nr database.

FIG 1 — Sequence comparison of plasmids harboring the mcr-1 gene. (a) Circular comparison between mcr-1-bearing IncI2 plasmid pLD67-1-MCR1 in strain LD67-1 in this study and three similar IncI2 plasmids in the NCBI nr database. pLD67-1-MCR1 was used as the reference in the outermost ring. (b) Circular comparison between mcr-1-carrying IncX4 plasmid pLD93-1-MCR1 in strain LD93-1 in this study and two similar IncX4 plasmids in the NCBI nr database. The outer circle with red arrows denotes annotation of reference plasmid pLD93-1-MCR1. (c) Circular comparison between three mcr-1-bearing IncHI2 plasmids and two similar IncHI2 plasmids in the NCBI nr database. (d) Linear comparison of the partial sequence containing mcr-1 of IncHI2 type plasmids (pLD22-1, pLD26-1, and pLD39-1) with two similar structures of plasmids pMCR_WCHEC050613 and p14EC029b in the NCBI nr database.