Figure 6.

Effect of NGF LTP at CA1 hippocampal synapses. (a) Superimposed pooled data showing the normalized changes in field potential amplitude (±SEM) induced by HFS (100 Hz, 1 s). LTP is enhanced following BK (1μm) and NGF (100 ng/mL) treatment, and the latter effect is reversed by HOE140 (100 nM) application. At least eight slices from four mice were used for each group tested. (b) Histograms show the relative increase in the fEPSP amplitude measured 50–60 min post-HFS under the different pharmacological conditions (* p < 0.05).