Table 1.
Effects of cytokines produced by eosinophils [120].
| Functions | Cytokines |
|---|---|
| Developmental functions | TGF-beta, IL-4 |
| Cell–cell interactions | Interleukins (1, 3, 4, 5, 6, 8, 9, 12, 13), IFN-γ, TGF-β, TNF-α, NGF, SCF, GM-CSF, CCL5, CCL11 |
| Metabolic homeostasis | IL-4, IL-13 |
| Immune polarization | Interleukins (4,5,10, 12, 13, 18, 25, 33), IFN-γ, TGF-β, CXCL9, CXCL10, CCL17, CCL22 |
| B cell maintenance | Interleukins (4, 5, 6, 10), TNF, APRIL |
| Tissue repair/remodeling | Interleukins (1β, 6, 13), PDGF, SCF, TGF-α, TGF-β, VEGF, CXCL1, CXCL10, CXCL12, CCL2, CCL3, CCL11 |