Table 5.
Parameter Predictors | HR (95% CI) | P Value |
---|---|---|
Composite of death, MI and stroke | ||
Age, y, vs ≤55 | <0.0001 | |
56–64 | 1.13 (0.82–1.55) | |
65–74 | 1.40 (1.02–1.91) | |
≥75 | 2.29 (1.64–3.18) | |
Cardiac catheterization for index event | 0.44 (0.35–0.55) | <0.0001 |
Country/region, vs China | <0.01 | |
Hong Kong, Singapore, South Korea | 0.71 (0.48–1.06) | |
India | 0.60 (0.46–0.80) | |
Malaysia, Thailand, Vietnam | 0.91 (0.66–1.25) | |
Discharge medications: diuretics | 1.62 (1.30–2.02) | <0.0001 |
eGFR group, mL/min per 1.73 m2, vs <30 | <0.0001 | |
≥30 to <60 | 0.66 (0.46, 0.96) | |
≥60 to <90 | 0.48 (0.33–0.70) | |
≥90 | 0.39 (0.27–0.58) | |
Final diagnosis of index admission event, vs STEMI | <0.0001 | |
NSTEMI | 1.25 (0.99–1.58) | |
UA | 0.64 (0.48–0.84) | |
Death | ||
Age, y, vs ≤55 | <0.0001 | |
56–64 | 1.57 (0.96–2.56) | |
65–74 | 1.95 (1.21–3.15) | |
≥75 | 4.35 (2.71–6.97) | |
Discharge medications: aldosterone inhibitors | 1.58 (1.10–2.28) | 0.01 |
Cardiac catheterization for index event | 0.40 (0.31–0.53) | <0.0001 |
Discharge medications: diuretics | 1.74 (1.27–2.38) | <0.001 |
eGFR group, mL/min per 1.73 m2, vs <30 | <0.0001 | |
≥30 to <60 | 0.66 (0.43–1.00) | |
≥60 to <90 | 0.36 (0.23–0.56) | |
≥90 | 0.28 (0.18–0.45) | |
Chronic DM therapy: oral agent | 0.69 (0.53–0.91) | <0.01 |
MI | ||
Cardiac catheterization for index event | 0.26 (0.19–0.37) | <0.0001 |
Country/region, vs China | <0.0001 | |
Hong Kong, Singapore, South Korea | 1.08 (0.64–1.83) | |
India | 0.12 (0.06–0.27) | |
Malaysia, Thailand, Vietnam | 0.99 (0.63–1.56) | |
Final diagnosis of index admission event, vs STEMI | <0.0001 | |
NSTEMI | 1.56 (1.08–2.25) | |
UA | 0.34 (0.20–0.57) | |
History: MI | 1.79 (1.22–2.64) | <0.01 |
Stroke | ||
Country/region, vs China | <0.05 | |
Hong Kong, Singapore, South Korea | 0.44 (0.14–1.40) | |
India | 0.22 (0.08–0.60) | |
Malaysia, Thailand, Vietnam | 0.66 (0.26–1.66) | |
Female | 2.46 (1.48–4.06) | <0.001 |
Any bleeding | ||
Chronic anemia | 5.38 (2.92–9.93) | <0.0001 |
Country/region, vs China | <0.0001 | |
Hong Kong, Singapore, South Korea | 0.43 (0.25–0.76) | |
India | 0.04 (0.01–0.13) | |
Malaysia, Thailand, Vietnam | 0.31 (0.16–0.59) |
Variable selection was done by stepwise procedure with the P value cutoffs for selection at P<0.01 and retention at P<0.20. For each outcome, the final model only included the variables shown in this table. DM indicates diabetes mellitus; eGFR, estimated glomerular filtration rate; HR, hazard ratio; MI, myocardial infarction; NSTEMI, non–ST‐segment–elevation myocardial infarction; STEMI, ST‐segment elevation myocardial infarction; and UA, unstable angina.