Figure 5. Effect of diabetes mellitus and plasminogen deletion on plasma renin, angiotensin II (ANGII), and aldosterone concentrations and kidney PRR (prorenin receptor) abundance in ANGII‐infused mice.

A, Renin, (B) ANGII, and (C) aldosterone levels were measured in plasma drawn from resting conscious mice after 8 days of ANGII infusion in diabetic wild‐type (WT STZ) and knockout mice (KO STZ) and control WT (WT VEH) and knockout mice (KO VEH). D, Immunoblot; E, densitometry analysis of the PRR protein abundance in kidney tissue homogenate. There were no differences between groups.