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. 2020 Nov 26;9(23):e018427. doi: 10.1161/JAHA.120.018427

Table 2.

Summary of AERP Comparisons Between Different AF Subtypes

Year of Publication, First Author Subjects, N Protocol Recording Location

BCL

(ms)

AERP

(ms), Controls

AERP

(ms), PAF

AERP

(ms), peAF

1991, Kumagai 48

12 peAF

12 controls

Decremental, 10‐ms steps HRA, CS 238±23 215±1*
1995, Capucci 21

25 PAF,

10 controls

Decremental, 1‐ms steps HRA, CS 600 231±36 193±2*
500 231±32 190±2*
400 234±34 178±4*
1998, Pandozi 44 14 peAF Decremental, 2‐ms steps RA (mean of 5 sites) 700 207±19
600 203±18
500 198±17
400 191±15
300 180±15
1999, Kamalvand 43

13 peAF,

8 controls

Decremental, 10‐ms steps, RAA 600 265 210*
MLRA 600 228 215
RAA 400 270 200*
MLRA 400 218 216
2000, Osaka 46 10 peAF, 10 controls Decremental, 5‐ms steps, 2× RA 600 247±25 224±13
RA 400 233±25 215±1*
2001, Brundel 23 13 controls, 13 PAF, 16 peAF RAA, LAA 600 291±53 222±1* 208±3*
500 277±42 224±2* 207±2*
400 252±34 216±2* 203±2*
300 224±16 202±20* 189±24*
250 184±5 185±19 172±17
2010, Centurion 25 58 PAF, 62 controls Decremental, 10‐ms steps RAA 500 215±29 208±2*
2013, Uhm 47

343 PAF,

140 peAF

Decremental, 1‐ms steps HRA 500 233±29 231±27
LRA 500 229±31 228±27
PCS 500 251±3 236±3
DCS 500 258±4 237±3
Mean of all locations 500 243±27 233±2
2016, Nguyen 45 28 PAF Incremental, 2‐ms steps HRA 600 310±51
PCS 600 289±36
DCS 600 289±50
Left PV 600 257±62
Right PV 600 265±62
Mean of all locations 600 283±30

AERP indicates atrial effective refractory period; BCL, basic drive cycle length; DCS, distal coronary sinus; HRA, high right atrium; LA, left atrium; LRA, low right atrium; MLRA, midlateral right atrial wall; PAF, paroxysmal atrial fibrillation; PCS, proximal coronary sinus; peAF, persistent atrial fibrillation; PV, pulmonary vein; RA, right atrium; and RAS, right atrial septum.

*

Significantly different from controls.

Significantly different between types of AF.