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. 2020 Dec 9;12(12):2935. doi: 10.3390/polym12122935

Table 4.

Comparing natural and synthetic hydrogels.

Comparing Natural and Synthetic Hydrogels
Galler et al., 2018 [325] - PEG
- Self-assembling peptide (SAPbio) and Puramatrix™)
In vitro
In vivo
- PEG was modified to be chemically cured (PEGchem) or light-cured (PEGlight),
- Biomimetic hydrogels (PEGbio) modified by cell adhesion motif and MMP-2.
- Self-assembling peptide (SAPbio) modified by cell adhesion motif and MMP-2.
DPSCs TGF-β1 In vitro viability was higher in natural materials. Scaffold degradation, odontoblast-like cell differentiation, tissue formation and vascularization were higher in natural materials in vivo.