Table 4.
Comparing Natural and Synthetic Hydrogels | ||||||
---|---|---|---|---|---|---|
Galler et al., 2018 [325] | - PEG - Self-assembling peptide (SAPbio) and Puramatrix™) |
In vitro In vivo |
- PEG was modified to be chemically cured (PEGchem) or light-cured (PEGlight), - Biomimetic hydrogels (PEGbio) modified by cell adhesion motif and MMP-2. - Self-assembling peptide (SAPbio) modified by cell adhesion motif and MMP-2. |
DPSCs | TGF-β1 | In vitro viability was higher in natural materials. Scaffold degradation, odontoblast-like cell differentiation, tissue formation and vascularization were higher in natural materials in vivo. |