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. 2020 Dec 11;12(12):1205. doi: 10.3390/pharmaceutics12121205
AAV Adeno-associated virus
ABC ATP-binding cassette protein
AMT Adsorptive-mediated transcytosis
BBB Blood–brain barrier
BBBD Blood–brain barrier disruption
BCRP Breast cancer resistance protein
BTB Blood–tumor barrier
CED Convection-enhanced delivery
CNS Central nervous system
CSF Cerebrospinal fluid
CVO Circumventricular organs
DIPG Diffuse intrinsic pontine glioma
EC Endothelial cells
EGFR Epidermal growth factor receptor
FDA Food and Drug Administration
FUS Focused ultrasound
GBM Glioblastoma miltiforme
GLUT1 Glucose transporter 1
HDAC Histone deacetylase
IGFR Insulin-like growth factor receptor
IR Insulin receptor
IT Intrathecal
LDLR Low-density lipoprotein receptor
LRP1 Low-density lipoprotein-related protein 1
MCT1 Monocarboxylate transporter 1
MNP Magnetic nanoparticles
MSC Mesenchymal stem cells
MRI Magnetic resonance imaging
MRP Multidrug resistance protein
NSC Neural stem cell
NVU Neurovascular unit
NVU/BBB Neurovascular unit/blood–brain barrier
PDGFR-β Platelet-derived growth factor-β
P-gp P-glycoprotein
PLGA poly(lactic-co-glycolic acid)
RMT Receptor-mediated transcytosis
TfR1 Transferrin receptor 1
TMT Transporter-mediated transcytosis
VEGF Vascular endothelial growth factor