Figure 2.

Developmental expression of five mRNA of cyp2 isoforms in zebrafish whole embryos and larvae from 4 to 144 h post-fertilization (hpf) in comparison with their expression in the livers of adults of both sexes. Results of cyp2ad2 (A), cyp2k18 (B), cyp2n13 (C), cyp2r1 (D) and cyp2y3 (E) are shown. An inset graph was added in embryonic and larval cyp2r1 expressions (D). “a” indicates a significant (p < 0.05) difference compared with male livers and “b” is a significant (p < 0.05) difference compared with female livers. Black letters indicate significantly lower expression in embryos or larvae compared with adult livers, and red letters indicate significantly higher expression in embryos or larvae compared with adult livers. n = 6.