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. 2020 Dec 10;9(12):1034. doi: 10.3390/pathogens9121034

Figure 2.

Figure 2

Host kinases manipulated by Chlamydia to promote survival. Schematic contains a summary of host kinases manipulated by Chlamydia to inhibit apoptosis. EB binding and entry activate PI3K and ERK1/2 to promote survival. TarP activates Erk1/2. Sequestration of PKC, 14-3-3β, PDPK1, and GSK3β work via different mechanisms to prevent apoptosis.