Table 3.
Strain | MLST | P-MMIC (mg/L)/B-MMIC (mg/L) | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Aerobiosis | Microaerobiosis | |||||||||||||
FEP | IPM | AZM | GEN | TOB | CIP | FEP | IPM | AZM | GEN | TOB | CIP | |||
PAO1 | ST549 | 1/128 | 1/8 | 16/8 | 4/16 | 0.5/2 | <0.25/2 | 1/512 | 0.5/>128 | 128/>512 | 4/>256 | 1/>256 | <0.25/512 | |
ATCC39324 | - | 2/>512 | 2/16 | 64/8 | 8/16 | 2/8 | <0.25/512 | 16/>512 | 2/>128 | 512/>512 | 16/>256 | 4/>256 | <0.25/>512 | |
Ps270 | ST412 | 8/>512 | 4/>128 | 256/>512 | 32/>256 | 1/>256 | 2/32 | 32/>512 | 32/>128 | >512/>512 | 64/>256 | 2/>256 | 4/>256 | |
Ps338 | 4/512 | 1/4 | 128/32 | 4/64 | 0.5/32 | 1/8 | 8/512 | 1/4 | 512/512 | 4/64 | 2/32 | 2/8 | ||
Ps178 | ST155 | 8/>512 | 2/32 | 32/8 | 16/16 | 2/2 | 2/64 | 8/>512 | 4/>128 | 512/>512 | 16/>256 | 2/>256 | 4/512 | |
Ps839 | 8/>512 | 1/16 | 128/64 | 32/32 | 4/4 | <0.25/8 | 8/>512 | 4/>128 | 512/>512 | 32/>256 | 4/>256 | 0.5/512 | ||
Ps845 | 4/>512 | 1/8 | 8/8 | 0.25/2 | 0.25/2 | <0.25/8 | 8/>512 | 4/>128 | 16/>512 | 1/>256 | 0.5/>256 | <0.25/256 | ||
W336 | ST235 | 64/>512 | 64/>128 | 32/16 | >256/>256 | 128/>256 | 64/512 | 128/>512 | 64/>128 | 512/>512 | >256/>256 | 256/>256 | 128/>512 | |
W342 | 16/>512 | 16/64 | 32/16 | >256/>256 | 4/64 | 64/512 | 16/>512 | 32/>128 | 512/>512 | >256/>256 | 8/128 | 64/>512 |
1 Abbreviations: MLST, multilocus sequence typing; P-MMIC, Planktonic Minimum Metabolic Inhibitory Concentrations; B-MMIC, Biofilm Minimum Metabolic Inhibitory Concentrations. FEP, cefepime; IPM, imipenem; AZM, azithromycin; GEN, gentamicin; TOB, tobramycin; CIP, ciprofloxacin. All experiments were performed in triplicate wells for each condition, and repeated at least three times.