Effect of HMDP and HMPH on semi-fasting blood glucose in mice fed a high-fat diet. The difference between the HFC and LFC groups was analyzed using repeated measures t-test. The treatment effect was analyzed using 1-way ANOVA with repeated measures, and differences among the HFC, HMDP70 and HMPH70 groups were determined using the least-squares means test. The results are presented as means ± SEM (n = 11–12) and the significance level was set to 0.05. ξ
p < 0.0001 compared to LFC. a,b Among the HFC, HMDP70 and HMPH70, values bearing different letters differ, p < 0.05. LFC, low-fat control diet; HFC, high-fat control diet; HMDP70, HFC diet with 70% of casein protein being replaced by the same amount of protein derived from herring milt dry powder; HMPH70, HFC diet with 70% of casein protein being replaced with the same amount of protein derived from herring milt protein hydrolysate.