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. 2020 Dec 11;9(12):4014. doi: 10.3390/jcm9124014

Table 1.

Number of operations for Graves’ disease of contributing institutions and corresponding complication rates.

No. of Operations for GD/Evaluation Period No. of Institutions
n = 78
No. of Patients with GD
n = 1808
Postoperative Hypoparathyroidism
n = 525
Postoperative RLNP (per NAR) Re-Operations Due to Bleeding
<10 38 (49%) 155 (8.6%) 72 (46.5%) 15/279 (5.4%) 1 (0.6%)
11–30 22 (28%) 411 (22.7%) 143 (34.8%) 42/772 (5.4%) 5 (1.2%)
31–50 7 (9%) 280 (15.5%) 62 (22.1%) 26/533 (4.9%) 3 (1.1%)
>51 11 (14%) 962 (53.2%) 248 (25.8%) 55/1845 (3.0%) 14 (1.5%)

The influence of center volume (cut-off > 30 operations for GD during the study period of 25 months) showed a significant reduction of hypoparathyroidism (p < 0.0005) and RLNP (p = 0.0229). The rate of reoperations due to bleeding was not influenced by the center volume. GD, Graves’ disease; RLNP, recurrent laryngeal nerve palsy; NAR, nerves at risk.