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. 2020 Dec 9;25(24):5801. doi: 10.3390/molecules25245801

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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The ameliorating effect of Nano-CUR on genotoxicity induced by TZ-ingested rats: (A) Fluorescence micrograph of bone marrow cells nuclei after the comet assay. The untreated rats (G1) (control) show no detectable DNA damage. The nuclei of TZ-ingested rats (G2*) appeared damaged. The nuclei of Nano-CUR ingested rats (G3) appeared to have no detectable DNA damage as control. The nuclei of (1 g Nano-CUR + 7.5 mg TZ-mix)-ingested rats appeared to have slight damage, the nuclei of (2 g Nano-CUR + 7.5 mg TZ-mix)-ingested rats appeared to have no detectable DNA damage. (B) Bar graph showing the tail DNA damage percentage in nuclei of bone marrow of all treated rats subjected to comet assay. Data are mean ± S.D. (n = 10, p < 0.05).