DTT	1,4-dithiothreitol
EDAC	N-(3-dimethylaminopropyl)-N′-ethylcarbodiimide
EDTA	ethylenediaminetetraacetic acid
EGTA	ethylene glycol-bis(2-aminoethylether)-N,N,N′,N′-tetraacetic acid
FBS	fetal bovine serum
HEPES	4-(2-hydroxyethyl)piperazine-1-ethanesulfonic acid
IFN-α	interferon alpha
IFN-β	interferon beta
IPTG	isopropyl-β-d-thiogalactoside
mAbs	monoclonal antibodies
MS	multiple sclerosis
OTP	Open Targets Platform
PBS	phosphate-buffered saline
PDB	Protein Data Bank
PMSF	phenylmethylsulfonyl fluoride; 2-ME, 2-mercaptoethanol
RA	rheumatoid arthritis
RAGE	receptor for advanced glycation end products
RU	resonance unit
SDS-PAGE	sodium dodecyl sulfate–polyacrylamide gel electrophoresis
SPR	surface plasmon resonance
sulfo-NHS	N-hydroxysulfosuccinimide
Tricine	N-[tris(hydroxymethyl)methyl]glycine
Tris	tris(hydroxymethyl)aminomethane
Usp2	mouse ubiquitin specific peptidase 2