Table 1.

Phenanthriplatin and cisplatin modulate gene regulation in A549 cells. Top 10 up- and downregulated DEGs for A549 phenanthriplatin versus A549 control. DEG data analysis: (p ≤ 0.05; q ≤ 0.05; log₂FC ≥ 0; FPKM ≥ 1 in ≥ 3 samples; average FPKM ≥ 1 minimum count: 10).

Gene (↑)	Log2FC	p-Value	q-Value	Gene (↓)	Log2FC	p-Value	q-Value
ATF3	5.986	≤0.0001	≤0.0001	PFKFB3	−4.236	≤0.0001	≤0.0001
TFF1	4.067	≤0.0001	≤0.0001	LPCAT1	−4.240	≤0.0001	≤0.0001
RBP4	3.324	≤0.0001	≤0.0001	DAPK1	−4.305	≤0.0001	≤0.0001
S100A6	2.806	≤0.0001	≤0.0001	RAI1	−4.330	≤0.0001	≤0.0001
TNFRSF10D	2.760	≤0.0001	≤0.0001	ZNF609	−4.484	≤0.0001	≤0.0001
C12orf75	2.695	≤0.0001	≤0.0001	PDE4D	−4.590	≤0.0001	≤0.0001
TFPI2	2.691	≤0.0001	≤0.0001	B4GALT5	−4.665	≤0.0001	≤0.0001
ATP5MD	2.678	≤0.0001	≤0.0001	SIN3A	−4.809	≤0.0001	≤0.0001
SNHG14	2.667	≤0.0001	≤0.0001	HMOX1	−4.968	≤0.0001	≤0.0001
S100A4	2.659	≤0.0001	≤0.0001	TNFRSF1A	−5.852	≤0.0001	≤0.0001