Table 3.
Dose (Recon Mode) and Reader 1–3 | Sensitivity % (95% CI) |
Specificity % (95% CI) |
PPV % (95% CI) |
NPV % (95% CI) |
---|---|---|---|---|
Dose 25 | ||||
AD3, AD5 | 100 (88–100) | 100 (88–100) | 100 (73–100) | 100 (87–100) |
FBP: | ||||
Reader 1 | 88.6 (72–96) | 92.3 (62–99) | 96.9 (82–99) | 75 (47–91) |
Reader 2 | 91.4 (76–98) | 100 (72–100) | 100 (87–100) | 81.3 (54–95) |
Reader 3 | 94.3 (80–99) | 100 (72–100) | 100 (87–100) | 86.7 (58–98) |
Dose 50 | ||||
AD3, AD5, FBP | ||||
Reader 1–3 | 100 (88–100) | 100 (72–100) | 100 (88–100) | 100 (72–100) |
Dose 75 | ||||
AD3, AD5, FBP | ||||
(Reader 1–3) | 100 (88–100) | 100 (72–100) | 100 (88–100) | 100 (72–100) |
Dose 25, 50, and 75 indicates the percentage of the original dose values; AD3 = ADMIRE 3; AD5 = ADMIRE 5; FBP = filtered back projection; CI, confidence interval; PPV, positive predicted value; NPV, negative predicted value.