Table 2.
Compound | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | |
---|---|---|---|---|---|---|---|---|---|---|---|
Drug-likeness | Lipinski violations | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Ghose violations | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | |
Veber violations | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | |
Egan violations | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | |
Muegge violations | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
Lead-likeness violations | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 1 | 1 | |
PAINS alerts | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
a All results were obtained from the SwissADMET webserver [35].