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. 2020 Dec 10;8(12):592. doi: 10.3390/biomedicines8120592

Table 1.

CD146 and soluble CD146 in immune diseases.

Pathology Membrane CD146 Soluble CD146
Cell Population Function Ref Fluid of Interest Role Ref
Systemic sclerosis Fibroblasts Protects from fibrosis Kaspi et al. [30] Serum Follow-up Kaspi et al. [30]
Th17 cells Migration Gabsi et al. [32]
Diabetes mellitus Tubular epithelial cells Not determined Wang et al. [38] Serum Follow-up Saito et al. [39]
Rheumatoid arthritis Lymphocytes Migration Pickl et al. [49] Synovial fluid Prognosis Neidhart et al. [47]
Inflammatory Bowel Disease Endothelial cells Not determined Bardin et al. [56] Serum Follow-up Bardin et al. [56]
Multiple sclerosis Th17 cells Migration Breuer et al. [70] CSF Not determined Duan et al. [11]