Table 3.
Distribution of Extended-spectrum beta-lactamases (ESBL) and non-beta-lactamase encoding genes in genotypically confirmed strains of ESBL producing Enterobacterales.
| Type of Resistance | Organisms | |||||||
|---|---|---|---|---|---|---|---|---|
| Escherichia coli, N = 53 (%) | Klebsiella pneumoniae, N = 69 (%) | Proteus mirabilis, N = 13 (%) | Citrobacter freundii, N = 12 (%) | Klebsiella oxytoca, N = 9 (%) | Enterobacter cloacae, N = 9 (%) | Proteus vulgaris, N = 3 (%) | Morganella morganii, N = 3 (%) | |
| ESBL | ||||||||
| TEM | 46 (86.8) | 58 (84.06) | 12 92.31) | 9 (75) | 7 (77.78) | 7 (77.78) | 3 (100) | 3 (100) |
| CTX-M | 39 (73.6) | 61 (88.41) | 8 (61.54) | 8 (66.67) | 6 (66.67) | 4 (44.44) | ND | ND |
| SHV | 29 (54.7) | 30 (43.48) | 2 (15.39) | 4 (33.33) | 7 (77.78) | 3 (33.33) | ND | ND |
| PER | 8 (15.1) | 13 (18.84) | 3 (23.08) | 3 (25) | 2 (22.22) | 3 (33.33) | 1 (33.33) | ND |
| VEB | 1 (1.89) | 5 (7.25) | 8 (61.54) | ND | 1 (11.11) | 2 (22.22) | ND | ND |
| PMQR | ||||||||
| qnr A | 3 (5.66) | ND | 8 (61.54) | ND | ND | ND | 2 (66.67) | ND |
| qnrB | 12 (22.6) | 36 (52.17) | ND | 6 (50) | 5 (55.56) | ND | ND | 1 (33.33) |
| qnrC | 4 (7.55) | ND | ND | ND | ND | ND | ND | ND |
| qnrD | 7 (13.2) | 17 (24.64) | ND | ND | 3 (33.33) | ND | ND | ND |
| qnrS | 11 (20.8) | 3 (4.35) | 9 (69.23) | ND | ND | 3 (33.33) | ND | ND |
| Aac-ib-cr | 32 (60.4) | 51 (73.91) | 7 (53.85) | 7 (58.33) | 6 (66.67) | 2 (22.22) | 3 (100) | ND |
| oqxA | 14 (26.4) | 58 (84.06) | 9 (69.23) | ND | 4 (44.44) | 2 (22.22) | ND | ND |
| oqxB | 21 (39.6) | 62 (89.86) | 8 (61.54) | ND | 3 (33.33) | ND | ND | ND |
| qepA | 5 (9.43) | ND | ND | ND | ND | ND | ND | ND |
| AME | ||||||||
| aac(3)-Ib | 2 (3.77) | 4 (5.8) | ND | 3 (25) | 1 (11.11) | 1 (11.11) | ND | ND |
| aac(3)-Ia | 6 (11.3) | ND | ND | 1 (8.33) | ND | ND | ND | ND |
| aac(3)-IIa | 18 (34) | 19 (27.54) | 1(7.69) | 3 (25) | 2 (22.22) | 3 (33.33) | ND | 1 (33.33) |
| aac(6′)-Ib | 28 (52.8) | 46 (66.67) | 3 (23.08) | 2 (16.67) | 4 (44.44) | 1 (11.11) | ND | 1 (33.33) |
| ant(2”)-Ia | 0 | 6 (8.7) | ND | ND | 1 (11.11) | 2 (22.22) | ND | ND |
| ant(3”)-Ia | 22 (41.5) | 17 (24.64) | 2 (15.39) | 3 (25) | ND | 1 (11.11) | 1 (33.33) | ND |
| ant(4”)-IIa | 8 (15.1) | 4(5.797) | 1 (7.69) | ND | ND | ND | ND | ND |
| aph(3′)-Ia | 16 (30.2) | 30 (43.48) | 1 (7.69) | ND | 1 (11.11) | ND | ND | ND |
| aph(3”)-Ib | 20 (37.7) | 15 (21.74) | 1 (7.69) | ND | 2 (22.22) | 2 (22.22) | ND | ND |
| armA | 5 (9.43) | 10 (14.49) | ND | ND | ND | ND | ND | ND |
| TMP-SMX | ||||||||
| sul1 | 35 (66) | 46 (66.67) | 6 (46.15) | 7 (58.33) | 6 (66.67) | 5 (55.56) | 2 (66.67) | 1 (33.33) |
| sul2 | 9 (17) | 6 (8.7) | ND | ND | 1 (11.11) | 1 (11.11) | ND | ND |
| dfrA1 | 20 (37.7) | 28 (40.58) | 2 (15.39) | 4 (33.33) | 1 (11.11) | 2 (22.22) | 1 (33.33) | 1 (33.33) |
ND: Not detected.