Gender [26,27] |
Males |
Females |
Onset [28] |
30–40 years of age |
20–30 years of age |
Site |
Distal colon [3] |
Any part of the gastrointestinal tract (GIT) [2] |
Complications |
Cryptitis, fistulas, severe bleeding [3], and colon cancer |
Strictures, abscesses, fistulas [2], colon cancer |
Smoking |
Protective role-reduced colectomy and sclerosing cholangitis [29] |
Threatening—leading to gut irritation, an impaired immune response, and respiratory disease [30] |
Post-Surgery |
Surgically curable but higher risk for adults above 50 years due to postoperative complications like infections and abscesses [31] |
Relapse even after the surgical removal of the affected portion and postoperative complications like short bowel syndrome [32] |