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. 2020 Dec 9;10(12):2460. doi: 10.3390/nano10122460

Table 1.

Comparison between Crohn’s disease (CD) and ulcerative colitis (UC).

Parameters UC CD
Gender [26,27] Males Females
Onset [28] 30–40 years of age 20–30 years of age
Site Distal colon [3] Any part of the gastrointestinal tract (GIT) [2]
Complications Cryptitis, fistulas, severe bleeding [3], and colon cancer Strictures, abscesses, fistulas [2], colon cancer
Smoking Protective role-reduced colectomy and sclerosing cholangitis [29] Threatening—leading to gut irritation, an impaired immune response, and respiratory disease [30]
Post-Surgery Surgically curable but higher risk for adults above 50 years due to postoperative complications like infections and abscesses [31] Relapse even after the surgical removal of the affected portion and postoperative complications like short bowel syndrome [32]