ECM: |
extracellular matrix |
PMN: |
pre-metastatic niche |
BMDC: |
bone marrow-derived cells |
MDSC: |
myeloid-derived suppressor cells |
TAM: |
tumor-associated macrophage |
EV: |
extracellular vesicles |
EMT: |
epithelial-to-mesenchymal transition |
CAF: |
cancer associated fibroblast |
HSC: |
hematopoietic stem cell |
BBB: |
blood–brain barrier |
IL-6: |
interleukin 6 |
IL-1β: |
interleukin-1β |
CXCL12/SDF-1 α: |
stromal cell-derived factor 1 |
IL-8: |
interleukin 8 |
VEGF: |
vascular endothelial growth factor |
G-CSF: |
granulocyte-colony stimulating factor |
MIF: |
macrophage migration inhibitory factor |
TIMP-1: |
tissue inhibitor of metalloproteinases 1 |
GM-CSF: |
granulocyte–macrophage colony-stimulating factor |
SAA: |
serum amyloid A |
TGF-β: |
transforming growth factor beta |
HIF-1: |
hypoxia-inducible factor 1 |
CCL2: |
CC-chemokine ligand 2 |
CCL5: |
chemokine ligand 5 |
CXCL1: |
C–X–C motif ligand 1 |
JAK: |
Janus kinase |
STAT3: |
signal transducer and activator of transcription 3 |
AKT: |
protein kinase B |
MAPK: |
mitogen-activated protein kinase |
IDO: |
indoleamine 2,3-dioxygenase |
PD-L1: |
programmed death ligand 1 |