Figure 4.

ZIP4⁺ cells exhibited higher tumor formation abilities compared to other groups of cells (A) Representative photographs of mice i.p. injected with PE04 ZIP4⁺, PE04 ALDH⁺, and PEA2 ZIP4⁺, cells with some tumor burdens are arrow-indicated. (B) Tumors generated from low numbers of ZIP4⁺ and ALDH⁺ cells (s.c. injected). (C) Representative photographs of IHC staining of ZIP4, ALDH1, and NOTCH3 in ZIP4⁺ and ALDH⁺ tumor sections. Scale Bar = 20 μm. The dark purple/brown or dark blue colored cells above the background are positive stained. Representative results are shown for more than three independent experiments.