. 2020 Dec 9;12(12):3700. doi: 10.3390/cancers12123700

Table 5.

The suggested regression models for the analysis of the relationship between continuous variables (i.e., continuous clinical parameters) and the change in the relative peak area of the N-glycan structures with their respective squared regression coefficient. Please note, the annotation of independent variables follows the nomenclature of Table 2, i.e., x12 stands for the alteration of relative peak area of peak #12.

Formalization of the Relationship	R²	#
$y ~ - 6.31 + 1.81 \cdot x 12 \pm 0.16 \cdot x 17 \cdot x 18 + 0.76 \cdot x 17 \cdot x 19 + (- 0.90) \cdot x 17 \cdot x 20 + 0.03 \cdot x 17 \cdot x 21 + (- 0.38) \cdot x 18 \cdot x 19 + 0.74 \cdot x 18 \cdot x 20 + (- 0.03) \cdot x 20 \cdot x 21$	0.99	Equation (1)
$y ~ 48.64 + 0.34 \cdot x 21 + 0.22 \cdot x 17 \cdot x 19 + (- 0.25) \cdot x 17 \cdot x 20 + (- 0.14) \cdot x 18 \cdot x 19 + 0.17 \cdot x 18 \cdot x 20 + 0.02 \cdot x 19 \cdot x 20$	0.95	Equation (2)
$y ~ 2.32 + 0.05 \cdot x 14 + 0.001 \cdot x 17 \cdot x 20 + 0.001 \cdot x 19 \cdot x 21$	0.81	Equation (3)
$y ~ 397250 + 1688 \cdot x 17 \cdot x 18 + (- 1408) \cdot x 17 \cdot x 19 + (- 1623) \cdot x 18 \cdot x 20 + 393 \cdot x 18 \cdot x 21 + 832 \cdot x 19 \cdot x 20$	0.77	Equation (4)
$y ~ 5.79 + 0.01 \cdot x 17 \cdot x 18 + (- 0.01) \cdot x 17 \cdot x 19 + 0.005 \cdot x 17 \cdot x 21 + (- 0.01) \cdot x 18 \cdot x 19 + 0.01 \cdot x 18 \cdot x 20 + (- 0.01) \cdot x 18 \cdot x 21 + 0.01 \cdot x 19 \cdot x 20 + 0.005 \cdot x 20 \cdot x 21$	0.99	Equation (5)
$y ~ 18.8 + (- 0.04) \cdot x 17 \cdot x 19 + 0.04 \cdot x 17 \cdot x 21 + (- 0.05) \cdot x 18 \cdot x 21 + 0.04 \cdot x 19 \cdot x 20$	0.96	Equation (6)