| ALK | anaplastic lymphoma kinase |
| CCI | Charlson comorbidity index |
| ccRCC | clear cell renal cell cancer |
| CDCs | collecting duct carcinomas |
| ChRCC | chromophobe renal cell cancer |
| CR | complete response |
| ctDNA | circulating tumor DNA |
| CXCR4 | CXC-chemokine receptor-4 |
| dBP | diastolic blood pressure |
| DOR | duration of response |
| EMA | European medical agency |
| ESMO | European society for medical oncology |
| FDA | food and drug administration |
| FFS | failure free survival |
| HIF | hypoxia-inducible factor |
| HLRCC | hereditary leiomyomata and renal cell cancer |
| ICI | immune checkpoint inhibitors |
| IFN | interferon |
| IL-2 | interleukin-2 |
| IMDC | International Metastatic RCC Database Consortium |
| ITT | intention to treat |
| NCCN | national comprehensive cancer network |
| ORR | objective response rate |
| OS | overall survival |
| PD-1 | programmed cell death-1 |
| PD-L1 | programmed cell death-ligand 1 |
| PFS | progression free survival |
| PRCC | papillary renal cell cancer |
| RCC | renal cell cancer |
| RFS | relapse free survival; |
| RMC | renal medullary carcinoma |
| ROS1, ROS | proto-oncogene 1 receptor tyrosine kinase |
| SEER | surveillance epidemiology and end results |
| TKIs | tyrosine kinase inhibitors |
| TMB | tumor mutational burden |
| TRCC | translocation renal cell carcinoma |
| TSC | tuberous sclerosis complex |
| TTF | time to treatment failure |
| TTR | time to treatment response |
| VEGFr | vascular endothelial growth factor receptor |
| VHL | Von Hippel-Lindau |