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. 2020 Dec 13;12(12):3750. doi: 10.3390/cancers12123750
ALK anaplastic lymphoma kinase
CCI Charlson comorbidity index
ccRCC clear cell renal cell cancer
CDCs collecting duct carcinomas
ChRCC chromophobe renal cell cancer
CR complete response
ctDNA circulating tumor DNA
CXCR4 CXC-chemokine receptor-4
dBP diastolic blood pressure
DOR duration of response
EMA European medical agency
ESMO European society for medical oncology
FDA food and drug administration
FFS failure free survival
HIF hypoxia-inducible factor
HLRCC hereditary leiomyomata and renal cell cancer
ICI immune checkpoint inhibitors
IFN interferon
IL-2 interleukin-2
IMDC International Metastatic RCC Database Consortium
ITT intention to treat
NCCN national comprehensive cancer network
ORR objective response rate
OS overall survival
PD-1 programmed cell death-1
PD-L1 programmed cell death-ligand 1
PFS progression free survival
PRCC papillary renal cell cancer
RCC renal cell cancer
RFS relapse free survival;
RMC renal medullary carcinoma
ROS1, ROS proto-oncogene 1 receptor tyrosine kinase
SEER surveillance epidemiology and end results
TKIs tyrosine kinase inhibitors
TMB tumor mutational burden
TRCC translocation renal cell carcinoma
TSC tuberous sclerosis complex
TTF time to treatment failure
TTR time to treatment response
VEGFr vascular endothelial growth factor receptor
VHL Von Hippel-Lindau