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. 2020 Dec 22;13:13055–13062. doi: 10.2147/OTT.S288332

Table 1.

Association Between PGC-1α/ERRα Expression and Clinicopathological Parameters in Patients with Ovarian Cancer

Clinical Features Total (n) PGC-1α Expression χ2 P ERRα Expression χ2 P PGC-1α/ERRα Expression χ2 P
High Low High Low High/High Neither High
Age, years 0.032 0.859 0.095 0.758 0.033 0.856
 <55 42 17 8 15 10 11 14
 ≥55 12 5 11 6 7 10
Tumor size, cm 3.459 0.063 0.119 0.73 1.073 0.3
 <10 41 21 5 17 9 13 13
 ≥10 8 7 9 6 5 10
Tumor differentiation 4.786 0.029 6.275a 0.027 5.451a 0.04
 Well, moderate 37 6 8 6 8 3 11
 Poor 18 5 19 4 14 9
FIGO stage 0.149 0.699 1.036 0.309 0.717 0.397
 Ⅰ–Ⅱ 41 14 5 10 9 7 12
 III–Ⅳ 15 7 15 7 11 11
Lymph node status 1.332a 0.425 5.772a 0.023 7.161a 0.021
 Absent 32 13 8 10 11 5 16
 Present 9 2 10 1 8 3
CA125, U/mL 0.497 0.481 4.388 0.036 5.802a 0.021
 <78 42 8 5 5 8 2 11
 ≥78 21 8 21 8 16 13
CA153, U/mL 2.844 0.092 2.085 0.149 3.635a 0.078
 <14.8 38 5 6 5 6 2 9
 ≥14.8 20 7 19 8 14 13
HE4, U/mL 0.296 0.67 5.625a 0.025 4.568a 0.05
 <75.5 34 6 3 2 7 1 8
 ≥75.5 19 6 17 8 13 12

Notes: aFisher test was performed. The rest of the scores were from Chi-square test.

Abbreviations: ERRα, estrogen-related receptor α; PGC-1α, peroxisome proliferator-activated receptor gamma coactivator 1-alpha.