Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Dec 11;21(24):9442. doi: 10.3390/ijms21249442

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Phenotypic analysis of the deleted subclones. (A,B) Deletion of the miR-371/372/373 cluster and the miR-371/372/373 promoter, respectively. Lt, proliferation; Middle, invasion; Rt, anchorage-independent growth. Upper, quantification; Lower, representative fields. Invasion, ×100; anchorage-independent growth, ×50. (C) Subcutaneous xenografts in nude mice. Four or eight tumors in each group. (D) Western blot analysis of DKK1 and β-catenin expression in parental cells and the cluster deleted subclones. (E) Invasion assay of parental cells and the c60 subclone after treatment of 60 mM si-Scr or si-DKK1 oligonucleotides for 48 h. par, parental cell. *, p < 0.05; ***, p < 0.001; ****, p < 0.0001.