Biomarker expression that differed between progressive and non-progressive patients of the Predictive Model cohort. A schematic diagram of the 37 biomarkers screened in the Predictive Model cohort and whether the concentration was increased (red), decreased, or unchanged (green) between progressive and non-progressive patients. Abbreviations: Albumin-creatinine ratio (ACR), cystatin-c (Cys-C), albuminuria (Alb), serum creatinine (sCr), estimated glomerular filtration rate (eGFR), fibrin degradation products (FDPs), uromodulin (Umod), neutrophil gelatinase-associated lipocalin (NGAL), kidney injury molecule-1 (KIM-1), chemokine ligand 5 (CCL5), carboxypeptidase A3 (CPA3), interleukin (IL), colony-stimulating factor 2 (CSF2), monocyte chemoattractant protein-1 (MCP-1), tumour necrosis factor (TNF), soluble TNF receptor (sTNFR), stem cell factor (SCF), protein carbonyl (PC), hepatocyte growth factor (HGF), collagen (Col), matrix metalloproteinase (MMP), basic fibroblast growth factor (bFGF).